Experimental Medicine EM
At the Department of Clinical and Experimental Medicine, Section of Nuclear
Medicine, a prototype of a tomograph scanner for small animals is installed,
which combines the modes SPECT, PET and CT. The processing techniques of
tomographic data acquired for the images reconstruction, possibly by jointly
using the data from both the emissive and the transmission modes, require high
processing power and storage for the matrices describing the system, that are
not always sparse. In particular, for the analysis of emissive images, we are
interested in the implementation of Expectation Maximization Maximum Likelihood
(EM-ML) techniques with penalty, introducing the scatter correction in the
matrix that describes the problem. This would allow to reconstruct the data
acquired with high-energy-photons emitting radioisotopes, such as 123-I or
188-Re, which add a background signal to sinograms: this is the signal that has
to be "stolen" for a suitable data reconstruction, making semi-quantitative or
quantitative analysis possible.
http://docente.unife.it/giovanni.di.domenico
Promoters: Mauro Gambaccini mauro.gambaccini@unife.it
http://docente.unife.it/mauro.gambaccini/