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Experimental Medicine EM

At the Department of Clinical and Experimental Medicine, Section of Nuclear Medicine, a prototype of a tomograph scanner for small animals is installed, which combines the modes SPECT, PET and CT. The processing techniques of tomographic data acquired for the images reconstruction, possibly by jointly using the data from both the emissive and the transmission modes, require high processing power and storage for the matrices describing the system, that are not always sparse. In particular, for the analysis of emissive images, we are interested in the implementation of Expectation Maximization Maximum Likelihood (EM-ML) techniques with penalty, introducing the scatter correction in the matrix that describes the problem. This would allow to reconstruct the data acquired with high-energy-photons emitting radioisotopes, such as 123-I or 188-Re, which add a background signal to sinograms: this is the signal that has to be "stolen" for a suitable data reconstruction, making semi-quantitative or quantitative analysis possible.

Principal investigator: Giovanni Di Domenico didomenico@fe.infn.it
http://docente.unife.it/giovanni.di.domenico
Promoters: Mauro Gambaccini mauro.gambaccini@unife.it
http://docente.unife.it/mauro.gambaccini/